Each system differs in terms of channel configuration, maximum number of site/animal(s), dual-color & optogenetics compatibility, and advanced features across seven distinct fiber photometry systems. 

The basic system is the original, photodetector-based technology with decade-long validation. The bundle-imaging systems use CMOS sensor(s) to record multiple fibers simultaneously. The rotary-integrated systems built-in mini cube (optics, LED, and detector) on the rotary joint, such that the detector turns with the animal, completely abolishing rotation-related artifacts. The wireless system is a cable-free solution that supports multiple interacting animals. The fluorescence lifetime system measures picosecond changes in lifetime and is ideal to measure tonic/baseline changes over long periods of time. Click this link for a comparison of all fiber photometry systems.