Miniaturized Fluorescence Microscopes

Miniature Fluorescence Microscope monitors with cellular resolution the activity of neural circuitry in freely moving animals (e.g., mice or rats). It can be combined with optogenetic stimulation for activity modulation within or outside its field of view.

1-color Deep Brain Fluorescence Microscope uses gradient-index relay lens to re-image fluorescence flashes of neuronal populations found as deep as 8 mm into the brain.

1-color Surface Fluorescence Microscope uses an aspheric lens to image up to 150 µm deep into the brain with a larger field of view and better imaging quality.

2-color Fluorescence Microscope allows for simultaneous imaging of GFP-like and RFP-like fluorophores either in deep-brain or surface configuration.