Miniaturized Fluorescence Microscopes

Miniature Fluorescence Microscopes monitor neural circuitry's neuronal activity in freely moving animals (e.g., mice or rats) with cellular resolution. They can be combined with optogenetic stimulation for activity modulation within or outside the field of view.

1-color Deep Brain Fluorescence Microscopy System image structures found up to 8 mm deep into the brain with gradient index (GRIN) relay lens cannulas. 1-color Surface Microscopy Systems are optimized to image up to 150 µm deep into the brain with a larger field of view and better imaging quality. 2-color fluorescence microscopy systems allow the simultaneous imaging of GFP-like and RFP-like fluorophores either in deep-brain or surface configuration.