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The simplest form of the fiber-optic patch cord is a single strand of optical fiber surrounded by a buffer and protective jacket with connectors at both ends.

The optical fiber core diameter and its numerical aperture (NA) define the coupling efficiency into the fiber.

The most popular optical fiber core diameters for optogenetics and fiber photometry experiments are those with 200 µm and 400 µm core diameters. As for the numerical aperture of the fiber, smaller 0.22 NA is suitable for laser light sources, while for incoherent light sources, like LEDs, it is recommended to use 0.5 NA and higher all the way from the light source to the sample.

 Comparison Table : Patch cord Optical Fiber Type
 Optical Fiber Type Borosilicate Silica/Silica Silica/Polymer Plastic
 Core Glass Glass Glass Plastic
 Cladding Glass Glass Polymer Polymer
 Numerical Aperture 0.66 0.22 - 0.37 0.48 - 0.57 0.50 - 0.63
 Flexibility Poor Good Good Excellent
 Auto-Fluorescence Good Excellent Good Poor
 RECOMMENDED USE :
 Fiber Photometry N/A
(too fragile)
Good* Good* Not recommended
(high AF)
 Optogenetics LED Source N/A
(too fragile)
Not recommended
(low NA)
Good BEST
 Optogenetics Laser Source N/A
(too fragile)
BEST Good Good

* For Fiber photometry, we recommend low-autofluorescence optical fiber patch cords.
Core/Cladding
Material
Core
Diameter
(μm)
Cladding
 (μm)
Buffer
(μm)
NA Fiber-Optic Code*
Silica/Silica 50 125 250 0.22 50/125/XXX-0.22
60 65 75 0.37 60/65/XXX-0.37
62.5 125 250 0.27 62.5/125/XXX-0.27
100 110 125 0.22 100/110/XXX-0.22
100 110 125 0.37 100/110/XXX-0.37
200 220 240 0.22 200/220/XXX-0.22
200 220 245 0.37 200/220/XXX-0.37
300 330 370 0.22 300/330/XXX-0.22
300 330 360 0.37 300/330/XXX-0.37
400 440 480 0.22 400/440/XXX-0.22
400 440 470 0.37 400/440/XXX-0.37
550 600 1040 0.22 550/600/XXX-0.22
600 660 710 0.22 600/660/XXX-0.22
600 660 710 0.37 600/660/XXX-0.37
Silica/Polymer 200 230 500 0.48 200/230/XXX-0.48
200 230 500 0.57 200/230/XXX-0.57
300 330 650 0.48 300/330/XXX-0.48
400 430 730 0.37 400/430/XXX-0.37
400 430 730 0.48 400/430/XXX-0.48
400 430 730 0.57 400/430/XXX-0.57
600 630 1040 0.48 600/630/XXX-0.48
Plastic/Plastic 240 250 - 0.50 240/250/XXX-0.50
240 250 - 0.63 240/250/XXX-0.63
480 500 - 0.50 480/500/XXX-0.50
480 500 - 0.63 480/500/XXX-0.63
735
750
- 0.50 735/750/XXX-0.50
735
750
- 0.63 735/750/XXX-0.63
960 1000 - 0.50 960/1000/XXX-0.50
960 1000 - 0.63 960/1000/XXX-0.63
1470 1500 - 0.50 1470/1500/XXX-0.50
1960 2000 - 0.50 1960/2000/XXX-0.50

* XXX is representative of the jacket code, see Jackets tab to choose the best one for your needs
Code Description Image Drawings
FC FC Connector with Zirconia Ferrule  border=
FCM FC Connector with Metal Ferrule  border=
FCA FC/APC Connector with Zirconia Ferrule*
 border=
SMA SMA Connector with Metal Ferrule  border=
ZF1.25 Zirconia Ferrule OD 1.25 mm  border=
ZF1.25(F) Zirconia Ferrule OD = 1.25 mm with Flange  border=
ZF1.25(FP) Zirconia Ferrule OD = 1.25 mm with Peek Flange  border=
ZF1.25(RF)
Zirconia Ferrule OD = 1.25 mm with Reduced Flange 1.6 mm
 border=
MF1.25 Metal Ferrule OD 1.25 mm  border=
MF1.25(F) Metal Ferrule OD 1.25 mm with Flange  border=
ZF2.5 Zirconia Ferrule OD = 2.5 mm  border=
ZF2.5(F) Zirconia Ferrule OD = 2.5 mm with Flange  border=
ZF2.5(FP) Zirconia Ferrule OD = 2.5 mm with Peek Flange  border=
MF2.5 Metal Ferrule OD = 2.5 mm  border=
MF2.5(F) Metal Ferrule OD = 2.5 mm with Flange  border=
CM3 M3 Connector  border=
CM3(P) M3 Connector Peek Plastic  border=
CM2 M2 Connector  border=
CM2(P) M2 Connector Peek Plastic  border=
SMC Slim Magnetic Connector  border=
Comparison Table : Protective Jacket
Image Code Description Color OD
(mm)
Linear mass
(g/m)
Flexibility Fiber break protection Fiber pull protection Proposed usage
900 Hytrel loose tube 0.9 Black* 0.9 0.5
Excellent
Low
Low
Cable to small freely-moving animal (mice)
1100
Hytrel loose tube 1.1 mm
Black* 1.1 0.5 Excellent
Low
Low Cable to small freely-moving animal (mice)
3000 PVC jacket 3 mm Black 3.0 5.8 Low Good Excellent General use cable
LWMJ Stainless monocoil with PVC 2.4 mm Black 2.4 7.5 Good
Good
Good Freely-moving animal light delivery with large mice or rat
PKMJ
Stainless monocoil with kevlar and PUR 3.0 mm
Black 3.0 11 Good
Excellent
Excellent Best compromise between flexibility and robustness
ARMO Stainless armor 2.3 mm Silver 2.3 9.2 Low Excellent Excellent Preferred for maximum robustness
ARBK Stainless armor with PVC 3 mm Black 3.0 15 Low Excellent Excellent Preferred for maximum robustness

* Other color available on request.
Jacket availability may vary with optical fiber type


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