Mono Fiber-optic Cannula
The Mono Fiber-optic Cannula is an assembly of a bare optical fiber, a fiber ferrule and a receptacle or a sleeve. One side of the ferrule is polished while the implantable part of the fiber protrudes from the opposite end of the ferrule. The ferrule is placed within the receptacle or sleeve to allow connection to the fiber-optic patch cord. The protruding fiber can be implanted into the body while the ferrule or the receptacle is attached to the skull. When the cannula is connected with the patch cord, it is possible to send light signals to and from tissue close to the fiber tip. It is imperative for in vivo optogenetics applications that the fiber-optic cannula allows for efficient, plug and play type connection to the fiber-optic patch cord.NOTES :
A receptacle is a mechanical holder that defines the positions of the fiber tip and guides the connecting ferrule to the optical coupling position. For Mono Fiber-optic Cannulas we offer zirconia sleeves as the simplest form of a receptacle, alongside M2, M3 and slim magnetic receptacles.
Low Profile Cannulas are designed to minimize the height over the animal's head. The patch cord connection is in the same axis as the animal's body instead of hanging over its head. This cannula allows for the fiber optic implantation in a standard stereotaxic dorso-ventral axis, but the interconnection are along the antero-posterior plane. This cannula design minimizes the pressure applied on the animal's head during the connection/disconnection of the patch cord. Furthermore, the Low Profile Cannula facilitates the motion of the animal’s head in restraint areas.
- The tolerance on the length of the protruding fiber is better than 0.1 mm.
- Sleeves required to connection with a patch cord are ordered separately.
- Stereotaxic Cannula Holder (SCH) for 1.25 and 2.5 mm diameter ferrule is available for implantation to securely hold the Mono Fiber-optic Cannulas.
- Receptacle adapters are available for M2 and M3 receptacles to use with SCH.
- A specific version is available for LPB90(P) receptacle.
- Low-Profile Cannula receptacle is only available with borosilicate optical fiber type.
Comparision Table for Cannulas Optical Fiber Type Fiber-optic Material Borosilicate Silica/Silica Silica/Polymer Plastic Core Glass Glass Glass Plastic Cladding Glass Glass Polymer Polymer Protective Layer - Polyimide - - Numerical Aperture 0.66 0.22 - 0.37 0.48 - 0.57 0.50 - 0.63 Chemical Resistance Good Excellent Poor Poor Mechanical Resistance Poor Excellent Good Good Scratch Resistance Good Excellent Poor Poor Auto-Fluorescence Good Excellent Good Poor RECOMMENDED USE : Fiber Photometry BEST Good Good Not recommended
Optogenetics (LED Source) BEST Not recommended
Good Good Optogenetics (Laser Source) Good BEST Good Good
Receptacle Type ZF1.25 - ZF2.5
MF1.25 - MF2.5
SM3 - SM3(P)
RM2 - RM2(P)
SMR LPB90(P) Connection type sleeve screw magnetic twist sleeve Transmission 80 % 80 % 70 % 60 % Protrusion Length (mm) 0 to 50 0 to 50 0 to 50 1.0 to 30 Protrusion Tolerance (mm) +/- 0.1 +/- 0.1 +/- 0.1 +/- 0.2 Angle (deg) 0 0 0 90 +/- 2 MRI compatible yes (zirconia only)
yes (peek version)
yes (peek version)
Core Material Core Diameter
NA Buffer Color Outer Layer CodeGlass 50 70 0.22 Yellow Polyimide 050/070-0.22 60 75 0.37 Yellow Polyimide
060/075-0.37 100 125 0.22 Yellow Polyimide
100/125-0.22 100 125 0.37 Yellow Polyimide
100/125-0.37 100 125 0.66 Clear Borosilicate
100/125-0.66 200 240 0.22 Yellow Polyimide
200/240-0.22 200 245 0.37 Yellow Polyimide
200/245-0.37 200 230 0.48 Clear Polymer
200/230-0.48 200 230 0.57 Clear Polymer
200/230-0.57 200 250 0.66 Clear Borosilicate 200/250-0.66 300 370 0.22 Yellow Polyimide
300/370-0.22 300 360 0.37 Yellow Polyimide
300/360-0.37 400 480 0.22 Yellow Polyimide
400/480-0.22 400 470 0.37 Yellow Polyimide
400/470-0.37 400 430 0.66 Clear Borosilicate 400/430-0.66 600 710 0.37 Yellow Polyimide 600/710-0.37Plastic 240* 250 0.63 Clear PMMA 240/250-0.63 480* 500 0.63 Clear PMMA 480/500-0.63
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