Mono Fiber-optic Cannula

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DESCRIPTION
SPECIFICATIONS
FIBER-OPTIC CODES
RECEPTACLE CODES
FIBER TIP

The Mono Fiber-optic Cannula is an assembly of a bare optical fiber, a fiber ferrule and a receptacle or a sleeve. One side of the ferrule is polished while the implantable part of the fiber protrudes from the opposite end of the ferrule. The ferrule is placed within the receptacle or sleeve to allow connection to the fiber-optic patch cord. The protruding fiber can be implanted into the body while the ferrule or the receptacle is attached to the skull. When the cannula is connected with the patch cord, it is possible to send light signals to and from tissue close to the fiber tip. It is imperative for in vivo optogenetics applications that the fiber-optic cannula allows for efficient, plug and play type connection to the fiber-optic patch cord.

A receptacle is a mechanical holder that defines the positions of the fiber tip and guides the connecting ferrule to the optical coupling position. For Mono Fiber-optic Cannulas we offer zirconia sleeves as the simplest form of a receptacle, alongside M2, M3 and slim magnetic receptacles.

Low Profile Cannulas are designed to minimize the height over the animal's head. The patch cord connection is in the same axis as the animal's body instead of hanging over its head. This cannula allows for the fiber optic implantation in a standard stereotaxic dorso-ventral axis, but the interconnection are along the antero-posterior plane. This cannula design minimizes the pressure applied on the animal's head during the connection/disconnection of the patch cord. Furthermore, the Low Profile Cannula facilitates the motion of the animal’s head in restraint areas.

NOTES :

The tolerance on the length of the protruding fiber is better than 0.1 mm.
Sleeves required to connection with a patch cord are ordered separately.
Stereotaxic Cannula Holder (SCH) for 1.25 and 2.5 mm diameter ferrule is available for implantation to securely hold the Mono Fiber-optic Cannulas.
Receptacle adapters are available for M2 and M3 receptacles to use with SCH.
A specific version is available for LPB90(P) receptacle.
Low-Profile Cannula receptacle is only available with borosilicate optical fiber type.
For more information about Fiber Tip, please refer to the section Fiber-optic Cannula in the solution section.

Comparision Table for Cannulas Optical Fiber Type
Fiber-optic Material	Borosilicate	Silica/Silica	Silica/Polymer	Plastic
Core	Glass	Glass	Glass	Plastic
Cladding	Glass	Glass	Polymer	Polymer
Protective Layer	-	Polyimide	-	-
Numerical Aperture	0.66	0.22 - 0.37	0.48 - 0.57	0.50 - 0.63
Chemical Resistance	Good	Excellent	Poor	Poor
Mechanical Resistance	Poor	Excellent	Good	Good
Scratch Resistance	Good	Excellent	Poor	Poor
Auto-Fluorescence	Good	Excellent	Good	Poor
RECOMMENDED USE :
Fiber Photometry	BEST	Good	Good	Not recommended (high AF)
Optogenetics (LED Source)	BEST	Not recommended (low NA)	Good	Good
Optogenetics (Laser Source)	Good	BEST	Good	Good

Receptacle Type	ZF1.25 - ZF2.5 MF1.25 - MF2.5	SM3 - SM3(P) RM2 - RM2(P)	SMR	LPB90(P)
Connection type	sleeve	screw	magnetic twist	sleeve
Transmission	80 %	80 %	70 %	60 %
Fiber Length (mm)	0 to 50	0 to 50	0 to 50	1.0 to 30
Length Tolerance (mm)	+/- 0.1	+/- 0.1	+/- 0.1	+/- 0.2
Angle (deg)	0	0	0	90 +/- 2

MRI compatible	yes (zirconia only)	yes (peek version)	no	yes (peek version)

Core Material	Core Diameter (μm)	Outer Diameter (μm)	NA	Buffer Color	Outer Layer	Code
Glass
	50	70	0.22	Yellow	Polyimide	050/070-0.22
	60	75	0.37	Yellow	Polyimide	060/075-0.37
	100	125	0.22	Yellow	Polyimide	100/125-0.22
	100	125	0.37	Yellow	Polyimide	100/125-0.37
	100	125	0.66	Clear	Borosilicate	100/125-0.66
	200	240	0.22	Yellow	Polyimide	200/240-0.22
	200	245	0.37	Yellow	Polyimide	200/245-0.37
	200	230	0.48	Clear	Polymer	200/230-0.48
	200	250	0.66	Clear	Borosilicate	200/250-0.66
	300	330	0.48	Clear	Polymer	300/330-0.48
	300	370	0.22	Yellow	Polyimide	300/370-0.22
	300	360	0.37	Yellow	Polyimide	300/360-0.37
	400	480	0.22	Yellow	Polyimide	400/480-0.22
	400	470	0.37	Yellow	Polyimide	400/470-0.37
	400	430	0.48	Clear	Polymer	400/430-0.48
	400	430	0.66	Clear	Borosilicate	400/430-0.66
	600	630	0.48	Clear	Polymer	600/630-0.48
	600	710	0.22	Orange	Polyimide	600/710-0.22
	600	710	0.37	Yellow	Polyimide	600/710-0.37
Plastic	240^*	250	0.63	Clear	PMMA	240/250-0.63
Plastic	480^*	500	0.63	Clear	PMMA	480/500-0.63

* Not offered with conical tip (C45, C60), 45^o mirror tip (MA45) or diffuse layer tip (DFL).

Description	Picture	Base Dimension	Mass	Code	Drawing
Zirconia Ferrule OD 1.25 mm		D1.25 mm	50 mg	ZF1.25
Zirconia Ferrule OD 1.25 mm with grooves		D1.25 mm	50 mg	ZF1.25(G)
Metal Ferrule OD 1.25 mm		D1.25 mm	50 mg	MF1.25
Zirconia Ferrule OD 2.5 mm		D2.5 mm	350 mg	ZF2.5
Zirconia Ferrule OD 2.5 mm with grooves		D2.5 mm	350 mg	ZF2.5(G)
Metal Ferrule OD 2.5 mm		D2.5 mm	400 mg	MF2.5
Receptacle with M2 thread Titanium		D2.5 mm	65 mg	RM2
Receptacle with M2 thread Peek Plastic		D2.5 mm	40 mg	RM2(P)
Receptacle with M3 thread Titanium		D3.2 mm	185 mg	SM3
Receptacle with M3 thread Peek Plastic		D3.2 mm	85 mg	SM3(P)
Slim Magnetic Receptacle Aluminium		3.2 x 4.9 mm	145 mg	SMR
Low Profile 90 deg		2.4 x 5.2 mm	120 mg	LPB90(P)

The light propagation into brain tissue will vary with the optical fiber type and the light source parameters. It can be visualized in this Application Note (the French version is available here).

Description	Drawing	Code	Note
Flat Tip		FLT
Angled Tip		A45 A60	Standard angles: 45°; 60° Other angles on request (max 60°)
Conical Tip		C60	Rounded tip thickness: ~0.1x to 0.2x core diameter Standard angle: 60° Other angles on request (max 60°)
45° mirror Tip		MA45
Diffuser layer Tip		DFL
Taper Tip		TAPER