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Fall 2025 Newsletter

Innovations in Optical Neuroscience

Doric Lenses’ latest fiber photometry, optogenetics & microscopy tools.
Check out FREE webinars, tutorial videos, quick tips, and more!


Fall 2025 Webinars

Join our monthly webinars and discuss live with our experts.

Fall 2025 Webinars

Webinar Registration


Fiber Photometry

FluoPulse™: Fluorescence Lifetime Fiber Photometry

FluoPulse™ is the latest innovation in fiber photometry. By capturing fluorescence lifetime shifts (instead of intensity), FluoPulse™ delivers expression-independent readouts of second messengers, metabolites, or kinase activity during naturalistic behaviors.

Measure intracellular signaling dynamics such as PKA activity (FLIM-AKAR), cAMP fluctuations (FLIM-Epac), and CaMKII conformational changes.

FluoPulse system

Wireless Fiber Photometry

Study the neural activity underlying social behaviors using Wireless Fiber Photometry.

danse™ Analysis Software

Accelerate your fiber photometry and behavior analyses without coding. Learn more about danse™.

Wireless photometry danse software

Request danse™ Free Trial


Microscopy

Doric Miniscope

Single-cell calcium imaging in freely-moving animals.

VoluScan™

4D live-cell imaging for organoids and assembloids.

Miniscope video VoluScan video

Doric Lenses offers a complete solution for single-cell fluorescence imaging in freely-behaving animals, including imaging cannulas, microscope body, rotary joint, and data analysis (danse™).

The latest Twist-on eFocus Microscopy systems include high-power optogenetics (>55 mW/mm²).

Leverage VoluScan™ to record single-cell activity in brain organoids and assembloids and study neural circuit development and dysfunction.


Optogenetics

LISER™ Light Source

A single high-power light source for all optogenetic needs. Learn more .

NEW — CamLoop

Real-time animal tracking for closed-loop optogenetics. Learn more .

LISER CamLoop

Quick Tips & Tutorial Videos

Q: Do you see mirroring effects in your photometry signal?

Mirroring effects occur when the wrong isosbestic point is used for a biosensor. Since May 2025, all Doric Gen.3 ilFMCs support flexible isosbestic points.

Find biosensor isosbestic points in Table 2 of Simpson et al. 2024 .

Isosbestic explanation

Q: Do you record multi-animal data in a single file?

danse™ now includes a Split operation to divide multi-animal data into single files with one click — compatible with all analysis pipelines.

danse split feature
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