Spring 2025 Newsletter
Innovations in Optical Neuroscience
Conferences, FREE webinars, scientific highlights, and product innovations from Doric Lenses.
Product Spotlight
Miniscope
Doric Lenses offers a complete solution for single-cell fluorescence imaging in freely behaving animals, including imaging cannulas, microscope body, rotary joint, and data analysis software (danseâ¢).
The latest Twist-on eFocus Microscopy systems combine seamlessly with high-power optogenetics (>55 mW/mm²).
Canadian Neuroscience Conference 2025
We will be in Toronto next week! Come visit our booth and explore the latest innovations in optical neuroscience, or book a meeting with our experts .
Webinar Schedule
Join our FREE webinar series, including a live question period with our experts.
Scientific Highlights
Separate anterior paraventricular thalamus projections differentially regulate sensory and affective aspects of pain
Chen et al. â Cell Reports (2025)
By combining Doricâs LISER⢠and rotary joints , Chen et al. optogenetically stimulated multiple opsins in freely moving mice. Distinct neuron populations in the anterior paraventricular thalamus were shown to regulate sensory versus affective components of pain.
Cortical representations of affective pain shape empathic fear in male mice
Choi et al. â Nature Communications (2025)
Using Doricâs Miniaturized Fluorescence Microscopy , researchers identified neural ensembles in the anterior cingulate cortex that encode observational fear. ACC projections to the periaqueductal gray selectively conveyed affective pain information and regulated empathic freezing behavior.
