Mono Fiber-optic Cannula

Zirconia ferrule 1.25 mm
  • Unit price per 

Ordering Code:
  • The Mono Fiber-optic Cannula is an assembly of a bare optical fiber, a fiber ferrule and a receptacle or a sleeve. One side of the ferrule is polished while the implantable part of the fiber protrudes from the opposite end of the ferrule. The ferrule is placed within the receptacle or sleeve to allow connection to the fiber-optic patch cord. The protruding fiber can be implanted into the body while the ferrule or the receptacle is attached to the skull. When the cannula is connected with the patch cord, it is possible to send light signals to and from tissue close to the fiber tip. It is imperative forĀ in vivoĀ optogenetics applications that the fiber-optic cannula allows for efficient, plug and play type connection to the fiber-optic patch cord.

    A receptacle is a mechanical holder that defines the positions of the fiber tip and guides the connecting ferrule to the optical coupling position. For Mono Fiber-optic Cannulas we offer zirconia sleeves as the simplest form of a receptacle, alongside M2, M3 and slim magnetic receptacles.

    Low Profile Cannulas are designed to minimize the height over the animal's head. The patch cord connection is in the same axisĀ as the animal's body instead ofĀ hanging over its head. This cannula allows for the fiber optic implantation in a standard stereotaxic dorso-ventral axis, but the interconnection are along the antero-posterior plane. This cannula design minimizes the pressure applied on the animal's head during the connection/disconnection of the patch cord. Furthermore, the Low Profile Cannula facilitates the motion of the animalā€™s head in restraint areas.

    NOTES :
      • The tolerance on the length of the protruding fiber is better than 0.1 mm.
      • Sleeves required to connection with a patch cord are ordered separately.
      • Stereotaxic Cannula Holder (SCH) for 1.25 and 2.5 mm diameter ferrule is available for implantation to securely hold the Mono Fiber-optic Cannulas.Ā 
      • Receptacle adapters are available for M2 and M3 receptacles to use with SCH.
      • A specific version is available for LPB90(P) receptacle.
      • Low-Profile Cannula receptacle is only available with borosilicate optical fiber type.
      • For more information about Fiber Tip, please refer to the section Fiber-optic Cannula in the solution section.

    Comparision Table for Cannulas Optical Fiber Type
    Fiber-opticĀ Material Borosilicate Silica/Silica Silica/Polymer Plastic
    Core Glass Glass Glass Plastic
    Cladding Glass Glass Polymer Polymer
    Protective Layer - Polyimide - -
    Numerical Aperture 0.66 0.22 - 0.37 0.48 - 0.57 0.50 - 0.63
    Chemical Resistance Good Excellent Poor Poor
    Mechanical Resistance Poor Excellent Good Good
    Scratch Resistance Good Excellent Poor Poor
    Auto-Fluorescence Good Excellent Good Poor
    Fiber Photometry BEST Good Good Not recommended
    (high AF)
    Optogenetics (LED Source) BEST Not recommended
    (low NA)
    Good Good
    Optogenetics (Laser Source) Good BEST Good Good
  • Receptacle Type ZF1.25 -Ā ZF2.5
    MF1.25 - MF2.5
    SM3 - SM3(P)
    RM2 - RM2(P)
    SMR LPB90(P)
    Connection type sleeve screw magnetic twist sleeve
    Transmission 80 % 80 % 70 % 60 %
    FiberĀ Length (mm) 0 to 50 0 to 50 0 to 50 1.0 to 30
    LengthĀ Tolerance (mm) +/-Ā 0.1 +/-Ā 0.1 +/-Ā 0.1 +/- 0.2
    Angle (deg) 0 0 0 90 +/- 2

    MRI compatible yes (zirconia only)
    yes (peek version)
    yes (peek version)

  • Core Material Core Diameter
    Outer Diameter
    NA Buffer Color Outer Layer Code
    50 70 0.22 Yellow Polyimide 050/070-0.22
    60 75 0.37 Yellow Polyimide
    100 125 0.22 Yellow Polyimide
    100 125 0.37 Yellow Polyimide
    100 125 0.66 Clear Borosilicate
    200 240 0.22 Yellow Polyimide
    200 245 0.37 Yellow Polyimide
    200 230 0.48 Clear Polymer
    200 250 0.66 Clear Borosilicate 200/250-0.66
    300 330 0.48 Clear Polymer 300/330-0.48
    300 370 0.22 Yellow Polyimide
    300 360 0.37 Yellow Polyimide
    400 480 0.22 Yellow Polyimide
    400 470 0.37 Yellow Polyimide
    400 430 0.48 Clear Polymer 400/430-0.48
    400 430 0.66 Clear Borosilicate 400/430-0.66
    600 630 0.48 Clear Polymer 600/630-0.48
    600 710 0.22 Orange Polyimide 600/710-0.22
    600 710 0.37 Yellow Polyimide 600/710-0.37
    240* 250 0.63 Clear PMMA 240/250-0.63
    480* 500 0.63 Clear PMMA 480/500-0.63
    * Not offered with conical tip (C45, C60),Ā 45o mirror tip (MA45) orĀ diffuse layer tip (DFL).

  • Description Picture Base Dimension
    Ā Code Drawing
    Zirconia Ferrule
    OD 1.25 mm
    D1.25 mm 50 mg Ā ZF1.25
    Zirconia Ferrule
    OD 1.25 mm with grooves
    D1.25 mm 50 mg Ā ZF1.25(G)
    Metal Ferrule
    OD 1.25 mm
    D1.25 mm 50 mg Ā MF1.25
    Zirconia Ferrule
    OD 2.5 mm
    D2.5 mm 350 mg Ā ZF2.5
    Zirconia Ferrule
    OD 2.5 mm with grooves
    D2.5 mm 350 mg Ā ZF2.5(G)
    Metal Ferrule
    OD 2.5 mm
    D2.5 mm 400 mg Ā MF2.5
    Receptacle with M2 thread
    D2.5 mm 65 mg Ā RM2
    Receptacle with M2 thread
    Peek Plastic
    D2.5 mm 40 mg Ā RM2(P)
    Receptacle with M3 thread
    D3.2 mm 185 mg Ā SM3
    Receptacle with M3 thread
    Peek Plastic
    D3.2 mm 85 mg Ā SM3(P)
    Slim Magnetic Receptacle
    SMR 3.2 x 4.9 mm 145 mg Ā SMR
    Low Profile 90 deg 2.4 x 5.2 mm 120 mg Ā LPB90(P)
  • Click to download the Application Note

    The light propagation into brain tissue will vary with the optical fiber type and the light source parameters.Ā  It can be visualizedĀ in thisĀ 
    Application NoteĀ (the French version is availableĀ here).

    Description Drawing Code Note
    Flat Tip FLT
    Angled Tip



    Standard angles: 45Ā°; 60Ā°

    Other angles on request (max 60Ā°)

    Conical Tip C60

    Rounded tip thickness: ~0.1x to 0.2x core diameter

    Standard angle: 60Ā°

    Other angles on request (max 60Ā°)

    45Ā° mirror Tip MA45
    Diffuser layer Tip DFL
    Taper Tip TAPERĀ